LC3-Associated Phagocytosis and Inflammation
نویسندگان
چکیده
منابع مشابه
LC3-Associated Phagocytosis (LAP): Connections with Host Autophagy
Autophagy is an intracellular degradative process with a number of roles, one of which can be the protection of eukaryotic cells from invading microbes. Microtubule-associated protein light-chain 3 (LC3) is a key autophagy-related protein that is recruited to the double-membrane autophagosome responsible for sequestering material intended for delivery to lysosomes. GFP-LC3 is widely used as a m...
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Burkholderia pseudomallei is the causative agent of melioidosis, a fatal infectious disease endemic in tropical regions worldwide, and especially prevalent in southeast Asia and northern Australia. This intracellular pathogen can escape from phagosomes into the host cytoplasm, where it replicates and infects adjacent cells. We previously demonstrated that, in response to B. pseudomallei infecti...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2017
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2017.08.012